Carlton, a 6-year-old boy, was playing on a sandy beach with his mother. He began to run along the shoreline when he stepped on the sharp edge of a shell, giving himself a deep cut on his foot. His mother washed his foot in the lake and put on his running shoe to take him home. One day later, Carltonâ€™s foot looked worse. The gash was red and painful. The foot was warm to touch and appeared swollen. Carltonâ€™s mom put some gauze over the wound and prepared to take him to the local community health clinic.
- What is the physiologic mechanism causing the wound to become red, hot, swollen, and painful? How is this different than the inflammatory response that might occur in an internal organ?
- What are the immunologic events that are happening at the local level during Carltonâ€™s acute inflammatory response?
- Which antiinflammatory medications could assist in decreasing the amount of inflammation to the site?